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Acai Berry and Cancer; Examining the Univeristy of Bradenton Leukemia Study
Posted on Monday, August 8, 2011
A quick Google search to get "acai berry and cancer" shows a world of confusing information from various dubious and credible sources. I certainly don't want to use in that confusion. Instead, what I thought I'd do as a minimum once per month is to translate a significant research paper into layman's terms. As a former college biochemistry professor, I'd like to are convinced demystifying technical subjects is certainly one of my strengths. Today I'm concentrating on the 2006 paper in that Journal of Agriculture and Nutrition Chemistry named "Acai Polyphenolics within their Glycoside and Aglycone Forms Stimulate Apoptosis of HL-60 Leukemia Cells" by way of David Del Pozo-Insfran, Susan S Percival and Stephen T Talcott of the University of Florida Department connected with Food Science and Human Nutrition. These links will take you to definitely the original sources: Acai and Leukemia from Univerisity regarding Florida and University of Florida's powerful and leukemia cells press releaseThis paper summarizes the capability of whole acai berry extracts to kill the specific type of human leukemia cell from a lab setting (not inside your body). Research almost always starts with 'cell-culture models'. HL-60 is incredibly specific type of human leukemia cell phone line. When a scientist hopes to do research on leukemia, they don't just draw blood from your cancer patient, rather they get their test cells from your numbered cell line such when HL-60. This ensures that quality cells are standardized and the results can be replicate later by way of another lab. This study desired to test the whole acai berry and several of its constituent parts. During the time this study was published which authors state that over 50% of the thousands of compounds in an acai berry pulp are unknown. (Dr. Alex Schauss and team have since documented the entire composition of the acai). So that you can test some of the diverse components of acai, the team used solubility to generate different fractions. Here is the way that works. Supposed that acai berry has only 6 underlying elements â€" A B C VE HAD E and F. Now thought you mash it up in addition to divide it into 3 storage containers. In the first container everyone add water, the second container you add vegetable oil and the third container you add alcohol consumption. In each case some of the mashed up acai will dissolve in the liquid. Let's suppose this is what happens: * Water â€" B, C and F dissolve * Petrol â€" A and D break up * Alcohol â€" A and F dissolveYou now take over 3 different fractions to test against the leukemia. Notice that E isn't in any of the fractions and that A and F are both in two different fractions. It is incredibly much a puzzle. You create several different fractions in hopes of narrowing down which components of the acai are responsible for your cell death. The team also desired to test the metabolites of ANY, B, C, D, E and also F. When the acai berry hits the stomach, the acid environment will immediately begin breaking down most of the components into new molecules â€" let us call them A', C 'and E'. It is very interesting to test these to get biological activity because maybe the main acai doesn't contain any components active against cancer and it is only in the interaction with the stomach acid likely formed. It is often hard to split up out the impact of the main foods from its metabolites. (This will be the hot debate in research around resveratrol. Once it hits the stomach it reduces rapidly. )Finally the University of Florida team desired to test different concentrations of each fraction so they diluted them to different concentrations. Now they have lots of fractions in the original acai berry extract in different concentrations and a lot of concentrations of the acid-hydroloyzed versions to test. The test fractions are combined with HL-60 human leukemia in a petri-dish and also the team observes what percent of the cells die across time. The particular findings are truly remarkable. * Each and every fraction showed some anti-cancer exercise * Two separate fractions (III and V within the paper) killed 82% of leukemia cells within 1 day * When the team diluted fractions III and also V by factor of 75 (1 part sample to A HUNDRED parts water) they still harmed 50% of leukemia cells in 1 day. * 100% of the getting rid of effects was obtained after SOME hours although they continued to monitor for 24 hours. * The full acai berry sample performed well, but not and also fractions III or V alone even though it contained everything in III and everything in V. OK, so maybe I acquired a little technical with which explanation, but I think you must highlight the complexity of foods science research. As much as we be informed on biochemistry and disease, we still cannot pinpoint which components of certain foods are in charge of certain biological activity. In many cases the good news is synergistic effect (the whole provides improvement over the some of its parts) and in most cases an antagonistic effect (one part provides improvement over the whole). The answer in the meantime is â€" lots of range. A little bit of every little thing. All of MonaVie's juice products are packed with acai and 18 other fruits. It is just good sense never to try to outsmart Mother Character, but rather get a little of everything. I personally discover these lab results against leukemia quite thrilling. 82% death in SOME hours? That's awesome. If you have access to even a portion of that effect in the body, you'd be giving our bodies an edge in the fight cancer. Those of us that do not own cancer can continue to watch the brand new research every year as we endeavor to narrow in on cures. Hopefully you appreciate your health enough to realize that prevention is a best bet. People suffering from cancer now must be made aware of any laboratory, animal or human study which might be relevant or promising. This is just not to give false hope. It's not necessarily to spread hype and misinformation or make a dollar at their own expense. It is to produce options. Acai berry is one such option with the risk/reward stacked high in its favor. What is the risk? Its a fruit that native people within the rain forest have eaten for years and years. What's the reward? (You fill in the blank)If you know someone affected by cancer, please bookmark, tweet or email this to them. Expertise is power
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